《欧洲心脏杂志》主编Prof. Crea

As we have already discussed, AI is a really important tool which can help in all fields of cardiovascular medicine. For instance，to improve diagnosis, as shown in the Chinese study mentioned before, in which AI-based assessment of the patient face predicted the presence of coronary artery disease. We have studies showing that AI-based reading of a simple electrocardiogram can predict the presence of left ventricular dysfunction or of aortic stenosis. Thus, the role of AI in diagnosis is extremely important. 

正如我们已经讨论的，人工智能是一个非常重要的工具，可以在心血管医学的所有领域提供帮助。例如，AI可以改进诊断，之前提到的中国研究就是如此，在该研究中，基于人工智能的患者面部评估可以预测冠心病的存在。我们有研究表明，基于人工智能的简单心电图解读可以预测左心室功能障碍或主动脉狭窄的存在。因此，人工智能在诊断中的作用极为重要。

And also the role of AI in the risk prediction with some elegant study coming from University of Oxford. The prognostic models, AI integrate perivascular adipose tissue(PVAT) information in, can predict cardiovascular risk much better than traditional risk factors. And AI can be extremely useful in predicting the response to treatment. AI is important in all areas of cardiovascular medicine.

此外，如牛津大学的研究所示，人工智能在风险预测方面可以发挥重要作用。将人工智能应用于血管周围脂肪组织（PVAT）的评估，在预测心血管风险方面的效果远优于传统风险因素。最后，人工智能在预测治疗反应方面极具价值。人工智能在心血管医学的所有领域都很重要。

Like other journals，our journal is flooded by papers based on artificial intelligence. We need to be cautious because not all studies and based on artificial intelligence are of top quality. A few months ago, we had published in an editorial in which we identify five quality indicators, which must be really fulfilled to have a top paper in artificial intelligence.

和其他期刊一样，我们的期刊也收到了大量基于人工智能的论文。我们需要保持谨慎，因为并非所有基于人工智能的研究都是高质量的。几个月前，我们发表了一篇特别文章，其中提出了五项质量指标。要发表一篇优秀的人工智能论文，必须满足这些指标。

Quality criterion 1, complete reporting and reproducibility of results. Complete reporting should include the detailed description of all steps of the modelling process.

标准一：结果的完整报告和可重复性。完整的报告应该包括对建模过程所有步骤的详细描述。

Quality criterion 2, clear intended clinical use of the AI-based model. The goal of the study should be clearly indicated and clinically relevant. 

标准二：基于人工智能的模型的明确临床用途。研究目标应明确指出，并与临床相关。

Quality criterion 3, rigorous model validation. The algorithm developed in the derivation cohort needs to be validated in an independent validation cohort.  

标准三：严格的模型验证。在推导队列中开发的算法需要在独立的验证队列中进行验证。

Quality criterion 4, sufficient sample size for AI model development and validation. A large sample size is needed for both the derivation and validation cohorts.

标准四：足够的样本量用于人工智能模型的开发和验证。推导队列和验证队列都需要较大的样本量。

Quality criterion 5, openness of data and software. The algorithm on which the study is based must be accessible to allow external validation. 

标准五：数据和软件的开放性。研究所依据的算法必须可供访问，以便进行外部验证。

In conclusion, AI is extremely important in the future of cardiovascular medicine but published studies must respect these five quality criteria. 

总之，人工智能在未来心血管医学的多个领域都将发挥极其重要的作用，但发表在期刊上的研究必须遵守这五个质量标准。

《欧洲心脏杂志》主编Prof. Crea

There are some important advices I would like to give to young Chinese cardiovascular researchers. The first is to preserve a high level of enthusiasm (even after a rejection of a submitted manuscript): enthusiasm is the fuel. When you are a young researcher, and you submit a paper, the probability of rejection is very high. It happened to me when I started. You must persist going through your learning curve. If you believe in what you do, you shouldn't stop after the rejection of your first papers. 

我想给年轻的中国心血管研究人员提供一些重要的建议。第一，要保持高度的热情（即使在稿件被拒之后）：热情是不竭动力。当你还是一名初出茅庐的研究人员时，论文被拒的可能性非常高。我刚开始的时候也这样。你必须坚持自己的学习曲线。如果你相信自己所做的事，就不应该因为最初的几篇论文被拒而停止。

When we come to the content of the manuscript, there are two main criteria we consider for acceptance. First, the methodology must be waterproof. But this is not terribly difficult. More difficult is to be innovative, to produce something which is new and impacting on clinical practice. These are the two criteria for a successful submission: strong methodology and innovation. 

在考虑稿件接收时，我们主要考量两个标准。首先，方法必须无懈可击。但这并不是特别困难。更难的是要具有创新性，要产出新颖且对临床实践有影响的研究成果。这是成功投稿的两个标准：方法严谨和创新性。

The mind of a young brilliant researcher is flooded by many questions. The challenge is to identify the questions which are clinically relevant. Not all questions who come to our mind are important. The difficulty is identifying which questions are important, which questions are impactful, and which questions must be addressed in order to change clinical practice.

青年才俊们的脑海中总会涌现出许多问题，他们的挑战在于识别出那些具有临床意义的问题。并非我们想到的所有问题都是重要的，难点在于判断哪些问题至关重要，哪些问题具有影响力，以及哪些问题必须得到解决才能改变临床实践。

Regarding manuscript presentation what is important is to make the manuscript as simple as possible, as straightforward as possible. The perfect manuscript must clarify what is the starting point, what is the current knowledge, and then how the new data presented in the manuscript improve our knowledge and impact on clinical practice.  An excellent manuscript must also identify the new questions generated by the new data. Our knowledge is a continuous progression. We publish studies which introduce elements of novelty and influence the practice, but they also generate new questions. Thus, in a good manuscript, the authors must also define what are the new questions generated by the manuscript they propose. If all this is respected, then the probability of acceptance is really good.

关于稿件的呈现，重要的是要尽量使稿件简洁明了。一篇完美的稿件必须阐明出发点、现有知识，然后说明稿件中提出的新数据如何增进我们的知识并对临床实践产生影响。一篇优秀的稿件还必须指出新数据所引发的新问题。我们的知识是一个不断发展不断深入的过程。我们发表的研究引入了新的元素，影响了实践，但它们也产生了新的问题。因此，在一篇好的稿件中，作者还必须定义他们所提出的稿件引发了哪些新问题。如果所有这些条件都做到了，那么稿件被接受的可能性就非常大。

《欧洲心脏杂志》主编Prof. Crea

As we discussed before, there are some areas of innovation which are particularly important. I would focus the showcase on one of these rapidly evolving areas. For instance, the showcase might be focused on the application of AI to risk prediction, or the application of AI to diagnosis. Another area might be a focus on nucleic acid-based treatments. There are many new treatments emerging in this direction. I think it is important to focus on these rapidly evolving areas. 

如前所述，有些创新领域尤为重要。我愿意将研究展播活动重点放在其中一个迅速发展的领域上。例如，研究展播可以聚焦于人工智能在风险预测中的应用，或人工智能在诊断中的应用。另一个领域可能是聚焦于基于核酸的治疗。这个方向正涌现出许多新的治疗方法。我认为，关注这些迅速发展的领域非常重要。