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北京时间8月27日至30日，2021年欧洲心脏病学会（ESC）大会将以在线会议的形式正式召开。届时，全球心脏病学界将齐聚一堂，进行与众不同的学习与交流体验。
本次大会即将公布4项新的临床实践指南、12场Late-Breaking Science（共40项研究）、19场Hot Lines (共21个研究报告)。
2021 New ESC Guidelines
ESC 2021
本届大会将公布四项新的ESC临床实践指南，为临床实践和更好的患者结果提出建议：心脏起搏、瓣膜性心脏病、心血管疾病预防、心力衰竭。
Late Breaking Science
ESC 2021
本届大会12场 Late-Breaking Science 共计发布40项研究的最新结果。
LBS 01. 心律失常专场：27 August 16:30-17:15
Channel 3 - Arrhythmias and Device Therap
LAAOS III - Surgical Atrial Fibrillation Ablation Evaluation
LAAOS III——外科房颤消融评估
Benefit of early rhythm control therapy in patients with asymptomatic AF -insights from EAST-AFNET 4
EAST-AFNET 4研究：对无症状房颤患者进行早期节律控制治疗的益处
Two-Year Outcomes with Leadless Pacing- Micra CED Results
Micra CED研究结果：植入无导线心脏起搏器的两年结果
LBS 02. 心力衰竭专场：27 August 16:30-17:15
Channel 6 - Heart Failure
VANISH Trial Results
VANISH试验结果
AVANTI: Dual VP-receptor Antagonism in HF
AVANTI：双VP受体拮抗剂用于心衰治疗
DAPA-HF
DAPA-HF研究
LBS 03. ACS 专场：27 August 16:30-17:15
Channel 2 - Latest Science
QUORUM : Quantum Genomics Firibastat (QGC001) or Ramipril after Acute Myocardial Infarction for Prevention of Left Ventricular Dysfunction
QUORUM：量子基因组公司的Firibastat (QGC001)或雷米普利用于预防急性心肌梗死后的左心室功能障碍
HUYGENS: Evolocumab and changes in plaque composition on OCT
HUYGENS：依洛尤单抗与OCT所示斑块组成的变化
ACCOST-HH: Adrecizumab in cardiogenic shock
ACCOST-HH: Adrecizumab用于心源性休克
Low-dose rivaroxaban during the acute phase of ACS - H-REPLACE Trial
H-REPLACE研究：小剂量利伐沙班在ACS急性期的使用
LBS 04. 基础&转化专场：28 August 15:30-16:15
Channel 4 - Basic Science
VASOAlLLERGO - Vascular dysfunction caused by allergic inflammation
VASOAlLLERGO：过敏性炎症引起的血管功能障碍
Key pathomechanisms of TTNtv-DCM
TTNtv基因-扩张型心肌病的关键病理机制
QGC606, a novel drug for treating heart failure
治疗心力衰竭的新药QGC606
Inhibition of ADAMTS13 rescues acquired von Willebrand syndrome in a preclinical left ventricular assist device animal model
在临床前左心室辅助装置动物模型中抑制 ADAMTS13 可挽救获得性 von Willebrand 综合征
LBS 05. COVID-19 专场：29 August 14:00-14:45
Channel 1 - COVID-19
Colchicine in Patients Hospitalized with COVID-19
秋水仙碱用于COVID-19住院患者
The Michelle trial: Medically Ill hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis with rivaroxaban ThErapy
Michelle试验：利伐沙班治疗用于COVID-19血栓形成的住院患者
Insights into the Effects of the COVID-19 Pandemic: Comprehensive Analysis from the GUIDE-HF Trial
来自GUIDE-HF试验的综合分析：COVID-19大流行影响的见解
PREPARE-IT: Icosapent Ethyl Versus Placebo in People Exposed to COVID-19
PREPARE-IT: 二十碳五烯酸乙酯与安慰剂在暴露于COVID-19人群中的使用情况
LBS 06. 高血压专场：29 August 14:00-14:45
Channel 2 - Late-Breaking Science
Efficacy of digital therapeutics for essential hypertension (HERB-DH1 pivotal study)
HERB-DH1关键研究：数字疗法治疗原发性高血压的疗效
Quadruple UltrA-low-dose tReaTment for hypErTension - QUARTE
QUARTE：四联超低剂量高血压治疗
DECIDE-Salt , effects of salt substitute and stepwise reduction of salt supply
DECIDE-Salt：盐替代品和逐步减少盐供应的影响
LBS 07. 影像专场：29 August 16:30-17:15
Channel 2 - Late-Breaking Science
The PACIFIC-II study: Diagnostic Comparison of SPECT, PET and MRI in Patients with Prior CAD
PACIFIC-II研究：SPECT、PET和MRI在既往冠心病患者中的诊断比较
FAABULOUS - 18F-Fluoride Assessment of Aortic Bioprosthesis Durability and Outcome
主动脉生物瓣膜耐久性和结果的18F-Fluoride评估
“EURECA” Use of Imaging in CCS
EURECA 在CCS中的应用
LBS 08. 预防专场：29 August 16:30-17:15
Channel 9 - Preventive Cardiology, Special Populations
NATURE-PCSK9 trial
NATURE-PCSK9试验
Fixed Dose Combination Therapies with or without Aspirin in Primary Prevention of Cardiovascular Disease
在心血管疾病的一级预防中，用或不用固定剂量阿司匹林的联合治疗
Explanations for contrasting results of REDUCE-IT vs. STRENGTH
REDUCE-IT vs. STRENGTH研究对比结果的解释
LBS 09. 瓣膜专场：29 August 16:30-17:15
Channel 2 - Late-Breaking Science
Repair or replace? TEER versus TMVI for secondary MR
修复或置换？用于继发MR的TEER vs. TMVI
Risk of Mortality Across the Spectrum of Untreated Aortic Stenosis
未经治疗主动脉瓣狭窄的死亡率
Inclusion-criteria of COAPT and MITRA-FR in EuroSMR-registry
在EuroSMR注册研究中COAPT和MITRA-FR的纳入标准
LBS 10. ACS和PCI专场：29 August 16:30-17:15
Channel 5 - Coronary Artery Disease - Acute Cardiac Care
Antiplatelet therapy in high bleeding risk patients with and without oral anticoagulant therapy after coronary stenting
冠状动脉支架置入术后口服或不口服抗凝药治疗高出血风险患者的抗血小板治疗
YNTAX II trial: five year follow-up
YNTAX II试验：五年随访
TWILIGHT-HBR: Ticagrelor Monotherapy in High Bleeding Risk Patients
TWILIGHT-HBR研究:替格瑞洛单药治疗高出血风险患者
LBS 11. 特殊人群专场：29 August 18:00-18:45
Channel 2 - Late-Breaking Science
WHF COVID-19 & CVD Global Study
WHF COVID-19和CVD全球研究
Mortality in hypertrophic cardiomyopathy by reason for diagnosis and genotype
肥厚性心肌病不同诊断原因及基因型的死亡率
Eligibility for early rhythm control in the general population and relation to outcomes in the UK Biobank
在英国生物样本库中，普通人群早期心律控制合格与治疗结局的联系
Event risk gradient by levels of psycho-affective burden after myocardial infarction
心肌梗死后不同心理-情感负担水平的事件风险梯度
LBS 12. 人工智能与数字健康专场：30 August 16:30-17:15
Channel 7 - Cardiovascular Imaging
cardAIc-cluster: Redefining beta-blocker response in heart failure
cardAIc-cluster：重新定义心力衰竭中的β受体阻滞剂应答
Upstream AF risk control with digital tool
利用数字化工具对上游房颤（AF）风险进行控制
cardAIc-ECG: ECG prediction of heart failure
cardAIc-ECG：心衰的心电图预测
Hotlines
ESC 2021
本届大会19场 Hot Lines专场，共计20项研究。
8/27 20:30
Dal-GenE: a pharmacogenetic cardiovascular trial of dalcetrapib
Dal-GenE: dalcetrapib的心血管药物遗传学试验（dalcetrapib，一种胆固醇酯转移蛋白CETP抑制剂）
8/27 23:25
GUIDE-HF: haemodynamic-guided management of heart failure – randomised arm primary outcomes
GUIDE-HF: 血流动力学指导下的心衰管理——随机组的主要结果
8/27 23:55
EMPEROR-Preserved: effect of empagliflozin on cardiovascular death and heart failure hospitalisations in patients with heart failure with a preserved ejection fraction, with and without diabetes
EMPEROR-Preserved研究：对于合并或不合并糖尿病的射血分数保留心衰患者，恩格列净对心血管死亡和因心衰住院的影响
8/28 00:10
EMPEROR-Pooled: effect of empagliflozin on serious adverse renal outcomes in chronic heart failure – a prospective alpha-protected, Individual patient-level pooled analysis
EMPEROR-Pooled研究：恩格列净对慢性心衰患者严重不良肾结局的影响-一项前瞻性、alpha保护的个体患者水平的汇总分析
8/28 00:40
Implantable cardiac monitors in high-risk post-infarction patients with cardiac autonomic dysfunction and moderately reduced left ventricular ejection fraction - A randomized trial
一项随机试验：植入式心脏监测仪用于心脏自主功能障碍且左心室射血分数中度降低的梗死后高危患者
8/28 20:00
MASTER DAPT: dual antiplatelet therapy after coronary stenting in high bleeding risk patients
MASTER DAPT研究：高出血风险患者冠脉支架植入术后的DAPT治疗
8/28 20:30
ENVISAGE-TAVI AF: edoxaban vs. vitamin K antagonists after TAVI in patients with atrial fibrillation
ENVISAGE-TAVI AF研究：房颤患者TAVI术后应用艾多沙班与维生素K拮抗剂的比较
8/28 23:25
FIGARO-DKD: finerenone in patients with chronic kidney disease and type 2 diabetes
FIGARO-DKD研究：非奈利酮在慢性肾脏病（CKD）合并2型糖尿病患者中的应用
8/28 23:50
FIDELITY Analysis: finerenone in mild-to-severe chronic kidney disease and type 2 diabetes
FIDELITY分析：非奈利酮在轻至重度慢性肾脏病（CKD）合并2型糖尿病患者中的应用
8/29 00:10
APAF-CRT: AV junction ablation and CRT in patients with permanent atrial fibrillation and narrow QRS
APAF-CRT研究：房室交界消融联合心脏再同步治疗（CRT）用于窄QRS波的永久性房颤患者
8/29 00:40
DECAAF II: efficacy of DE-MRI-guided fibrosis ablation vs. conventional catheter ablation of persistent atrial fibrillation
DECAAF II研究：比较延迟增强核磁共振（DE-MRI）指导下的纤维化消融与常规导管消融对持续性房颤的疗效
8/29 20:00
TOMAHAWK: immediate angiography after out-of-hospital cardiac arrest
TOMAHAWK研究：院外心脏骤停后直接血管造影
8/29 20:30
RIPCORD 2: does routine pressure wire assessment influence management strategy of coronary angiography for diagnosis of chest pain?
RIPCORD 2研究：常规压力导丝评估是否影响冠脉造影诊断胸痛的管理策略
8/29 23:25
ACST-2: stenting vs. surgery for tight carotid stenosis
ACST-2研究：支架置入术与手术治疗颈动脉极度狭窄的比较
8/29 23:55
LOOP Study: screening for AF with an implantable loop recorder to prevent stroke
LOOP Study研究：使用埋藏式心脏事件记录器筛查房颤以预防卒中
8/30 00:25
SSaSS: Salt Substitute and Stroke Study into the effect of salt substitutes on cardiovascular events and death
SSaSS盐替代品与卒中研究：盐替代品对心血管事件和死亡的影响
8/30 20:00
IAMI: Influenza Vaccination after Myocardial Infarction randomised tria
IAMI研究：心梗后接种流感疫苗的随机试验
8/30 20:30
PRONOUNCE: comparing cardiovascular safety of degarelix vs. leuprolide in patients with advanced prostate cancer and cardiovascular disease
PRONOUNCE研究：比较地加瑞克与亮丙瑞林用于晚期前列腺癌合并心血管疾病患者的心血管安全性
8/30 23:25
STEP Study: intensive vs. standard blood pressure control among older hypertensive patients
STEP 研究：老年高血压患者中强化与标准血压控制的比较
8/30 23:55
Amulet IDE: Amplatzer Amulet left atrial appendage occluder randomised controlled trial
Amulet IDE研究：Amplatzer Amulet 左心耳封堵器随机对照试验
8/31 00:25
STOPDAPT-2 ACS: one-month dual antiplatelet therapy followed by clopidogrel monotherapy in acute coronary syndrome
STOPDAPT-2 ACS研究：ACS患者1个月DAPT治疗后氯吡格雷单药治疗
来源：POCKET IN
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