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第66届美国血液学年会(ASH 2024)将于2024年12月7-10日在美国圣迭戈召开。ASH年会是全球血液学领域大规模全面涵盖恶性与非恶性血液病学的国际盛会,每年都会吸引来自全球100多个国家的25000余名血液学家和其他相关医疗保健专业人士参会。
今年,中国医学论坛报今日血液特别策划“中国之声,全球视野——ASH 2024专题报道”,通过中国医学论坛报融媒体平台展示全球血液学领域的最新研究进展和突破性临床数据,并通过视频连线重磅专家,解析研究成果,指导中国临床实践;前方记者还将与中国知名专家和学者在会议现场进行面对面交流,采写独家报道,第一时间与读者分享。请大家持续关注!
摘要号:97
英文标题:JAK/Rock Inhibitor Rovadicitinib for Glucocorticoid-Refractory or -Dependent Chronic Graft-Versus-Host Disease: Updated Results of Multicenter, Phase 1b/2a Trial
时间:Saturday, December 7, 2024: 9:30 AM
报告人:Yanmin Zhao
摘要号:99
英文标题:A Phase II Study to Evaluate the Efficacy and Safety of Pimicotinib (ABSK021) in Chronic Graft Versus Host Disease (cGvHD) after 1 or More Lines of Systemic Treatment
时间:Saturday, December 7, 2024: 10:00 AM
报告人:Depei Wu
摘要号:101
英文标题:Multiomic Analyses Uncover Immune Signatures of Steroid-Refractory Graft-Versus-Host Disease
时间:Saturday, December 7, 2024: 10:30 AM
报告人:Zengkai Pan
摘要号:477
英文标题:Safety and Efficacy of Tgrx-678, a Potent BCR::ABL1 allosteric Inhibitor, in Patients with Tyrosine Kinase Inhibitor Resistant and/or Intolerant Chronic Myeloid Leukemia: Updated Results of Phase 1 Study Tgrx-678 -1001
时间:Sunday, December 8, 2024: 10:00 AM
报告人:Qian Jiang
摘要号:480
英文标题:Olverembatinib As Second-Line (2L) Therapy in Patients (pts) with Chronic Phase-Chronic Myeloid Leukemia (CP-CML)
时间:Sunday, December 8, 2024: 10:45 AM
报告人:Li Weiming
摘要号:304
英文标题:Hetrombopag Added to Immunosuppressive Therapy in First-Line Treatment of Severe Aplastic Anemia: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial
时间:Saturday, December 7, 2024: 4:45 PM
报告人:Fengkui Zhang
摘要号:681
英文标题:Safety and Efficacy of Bicistronic CD19/CD22 CAR T Cell Therapy in Childhood B Cell Acute Lymphoblastic Leukemia
时间:Sunday, December 8, 2024: 5:00 PM
报告人:Hua Zhang
摘要号:682
英文标题:CD19 CAR T-Cell Therapy in Refractory Autoimmune Hemolytic Anemia
时间:Sunday, December 8, 2024: 5:15 PM
报告人:Ruonan Li
摘要号:683
英文标题:Sequential Infusion of Anti-CD19 and Anti-BCMA Chimeric Antigen Receptor T-Cells: A Promising Treatment Strategy for Refractory Immune-Mediated Platelet Transfusion Refractoriness
时间:Sunday, December 8, 2024: 5:30 PM
报告人:Yunju Ma
摘要号:378
英文标题:A Multi-Center Clinical Trial of Allogeneic Hematopoietic Stem Cell Transplants in Transfusion Dependent Thalassemia
时间:Saturday, December 7, 2024: 5:15 PM
报告人:Rongrong Liu
摘要号:711
英文标题:Preliminary Efficacy and Safety Results of TQB3473, a Novel Syk Inhibitor, in Adult Patients with Immune Thrombocytopenia (ITP)
时间:Monday, December 9, 2024: 11:00 AM
报告人:Hu Zhou
摘要号:712
英文标题:Updated Outcome from Biomarker MSC-C5b-9-Guided All-Trans Retinoic Acid Treatment for Resistant/Recurrent ITP: A Multicenter, Randomized, Open-Label, Phase 3 Clinical Trial
时间:Monday, December 9, 2024: 11:15 AM
报告人:Menglin Li
摘要号:663
英文标题:Decitabine Plus All-Trans Retinoic Acid Versus Decitabine Monotherapy for Myelodysplastic Syndromes with Excess Blasts: A Multicentre, Randomized Controlled Trial
时间:Sunday, December 8, 2024: 5:00 PM
报告人:Hongyan Tong
摘要号:1049
英文标题:Mini-Dosed Blinatumomab Maintenance Therapy Following Allogeneic Hematopoietic Stem Cell Transplantation in Acute B-Cell Lymphoblastic Leukemia
时间:Monday, December 9, 2024: 5:30 PM
报告人:Jie Ji
摘要号:1050
英文标题:Updated Results from a Phase Ⅱ Clinical Trial:Safety and Efficacy of Azacitidine and Chidamide Maintenance after Allogeneic Hematopoietic Stem Cell Transplantation for Patients with High-Risk Acute Myeloid Leukemia
时间:Monday, December 9, 2024: 5:45 PM
报告人:Rui Huang
摘要号:91
英文标题:Rituximab, Lenalidomide, and Zanubrutinib (ZR2) with Sequential CAR-T Cell As First-Line Therapy for High-Risk Large B Cell Lymphoma
时间:Saturday, December 7, 2024: 9:30 AM
报告人:Mingming Zhang
摘要号:92
英文标题:IL-10 Expressing CD19 CAR-T Cells Induce Complete Remission and Improve Long-Term Protection in Relapsed or Refractory B-Cell Hematological Malignancies
时间:Saturday, December 7, 2024: 9:45 AM
报告人:Jingjing Ren
摘要号:956
英文标题:A Highly Selective and Orally Bioavailable CK1α Molecular Glue Degrader Targets B-Cell Lymphoma Cells
时间:Monday, December 9, 2024: 4:45 PM
报告人:Ran Kong
摘要号:958
英文标题:KPT-330 Combined with Radiation Therapy: Effective Central Nervous System Lymphoma Treatment with Reduced Neurotoxicity
时间:Monday, December 9, 2024: 5:15 PM
报告人:Bingzong Li
摘要号:960
英文标题:CD93+ Myeloid Cells Suppress T-Cell-Mediated Anti-Tumor Immunity
时间:Monday, December 9, 2024: 5:45 PM
报告人:Hui Yu
摘要号:836
英文标题:Venetoclax Combined with Hag Regimen in Newly Diagnosed ETP-ALL: A Prospective, Multicenter, Phase 2 Trial
时间:Monday, December 9, 2024: 3:00 PM
报告人:Shanshan Suo
摘要号:839
英文标题:Tucidinostat Plus Pediatric-Inspired Chemotherapy As First-Line Therapy for Newly Diagnosed ETP-ALL/Lbl: An Open-Label, Single-Arm, Phase 2 Trial
时间:Monday, December 9, 2024: 3:45 PM
报告人:Jieping Lin
摘要号:986
英文标题:Final Analysis of a Phase 1 Study of Zanubrutinib Plus Lenalidomide in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
时间:Monday, December 9, 2024: 4:45 PM
报告人:Zheng Song
摘要号:806
英文标题:Rovadicitinib in Patients with Hemophagocytic Lymphohistiocytosis: A Single Arm, Open-Label, Phase I Study
时间:Monday, December 9, 2024: 3:00 PM
报告人:Zhao Wang
摘要号:810
英文标题:Pharmacological and Mechanism Study of a New RIPK1 Inhibitor Via Necroptosis to Treat Hemophagocytic Lymphohistiocytosis
时间:Monday, December 9, 2024: 4:00 PM
报告人:Jinbing Zhu
摘要号:1028
英文标题:A Single-Center, Single-Arm, Phase I Clinical Trial of Anti-BCMA/GPRC5D Bispecific CAR T-Cells in Patients with Refractory and Relapsed Multiple Myeloma with Extramedullary Disease
时间:Monday, December 9, 2024: 4:45 PM
报告人:Ling Qiu
摘要号:921
英文标题:A Novel Generation of Anti-CD7 Universal CAR-T Therapy for Patients with Relapsed or Refractory CD7 Positive T-ALL/Lbl: A Phase I Clinical Trial
时间:Monday, December 9, 2024: 3:15 PM
报告人:Yongxian Hu
摘要号:923
英文标题:A Prospective Investigator-Initiated Phase 1/2 Study of BCMA/CD19 Dual-Targeting CAR T Therapy in Patients with Relapsed/Refractory Multiple Myeloma Including Those with Extramedullary Disease
时间:Monday, December 9, 2024: 3:45 PM
报告人:Hua Jiang
摘要号:484
英文标题:Rovadicitinib in Patients with Myelofibrosis Who Were Refractory or Relapsed or Intolerant to Ruxolitinib: A Single Arm, Multicenter, Open-Label, Phase Ib Study
时间:Sunday, December 8, 2024: 10:15 AM
报告人:Chunkang Chang
摘要号:486
英文标题:First-in-Human Phase I/IIa Safety and Efficacy of Flonoltinib Maleate, a New Generation of JAK2/FLT3 Inhibitor in Myelofibrosis
时间:Sunday, December 8, 2024: 10:45 AM
报告人:Lijuan Chen
摘要号:1002
英文标题:The Efficacy and Safety of Selinexor in Combination with Ruxolitinib in Ruxolitinib-Treated Myelofibrosis Patients: The Interim Analysis of a Prospective, Open-Label, Multicenter, Parallel-Cohort, Phase 2 Study
时间:Monday, December 9, 2024: 5:45 PM
报告人:Minghui Duan
摘要号:832
英文标题:TENT5C As a Target of Chromatin Remodeler SMARCA2 Participates BTK Inhibitor Resistance in Mantle Cell Lymphoma By Regulating ATP Metabolism
时间:Monday, December 9, 2024: 3:30 PM
报告人:Yuting Yan
摘要号:833
英文标题:ST6GALNAC4 Promotes Diffuse Large B-Cell Lymphoma Progression Via Mediating Sialylation of Bmpr-1B at Thr24
时间:Monday, December 9, 2024: 3:45 PM
报告人:Yu Zhang
摘要号:89
英文标题:Targeted-Delivery Strategy of Engineered EV Functionalized By Anti-CD3/CD19 Bi-Specific T-Cell Engager in Treating B-Cell Malignancies
时间:Saturday, December 7, 2024: 10:30 AM
报告人:Xiuiu Yang
摘要号:437
英文标题:ERAD Activity Distinguishes the Functional Heterogeneity of Hematopoietic Stem Cells
时间:Sunday, December 8, 2024: 10:30 AM
报告人:QinLu Peng
摘要号:438
英文标题:SNORD113-114 Cluster Maintains Hematopoietic Stem Cell Self-Renewal Via Orchestrating the Translation Machinery
时间:Sunday, December 8, 2024: 10:45 AM
报告人:Hui Wang
摘要号:1044
英文标题:A Multicenter Randomized Controlled Trial of Low-Dose Ruxolitinib for Gvhd Prophylaxis in Haploidentical Hematopoietic Stem Cell Transplantation
时间:Monday, December 9, 2024: 5:45 PM
报告人:Hengwei Wu
摘要号:38
英文标题:The TFG-ROS1 Fusion Is an Oncogenic Driver of Human Myeloid Leukemia
时间:Saturday, December 7, 2024: 9:45 AM
报告人:Jie Sun
摘要号:893
英文标题:Venetoclax Plus Dexamethasone As First-Line Treatment for t(11; 14) Light-Chain Amyloidosis: Preliminary Result of a Phase II Prospective, Multicenter, Single-Arm Study
时间:Monday, December 9, 2024: 3:45 PM
报告人:Kaini Shen
摘要号:222
英文标题:Prospective Study of Avapritinib in Patients with Relapsed/Refractory or MRD-Positive Core-Binding Factor Acute Myeloid Leukemia with KIT Mutations
时间:Saturday, December 7, 2024: 3:15 PM
报告人:Xueqing Dou
摘要号:538
英文标题:Polycomb Repressive Complex 2 Regulates Differentiation-Stage-Specific Autophagy Gene Expression and Safeguards Normal Erythropoiesis
时间:Sunday, December 8, 2024: 12:45 PM
报告人:Jiazhuo Li
摘要号:539
英文标题:A Novel Role of LKB1 in Erythroblast Enucleation
时间:Sunday, December 8, 2024: 1:00 PM
报告人:Yuanlin Xu
摘要号:345
英文标题:Mitochondrial Transcriptional-Translational Conflict Contributes to Defective Erythropoiesis and Disease Progression in Splicing Factor Mutant Myelodysplastic Syndromes
时间:Saturday, December 7, 2024: 4:30 PM
报告人:Qiaoli Li
摘要号:843
英文标题:The Mutated of KRAS gene Determine the Fate of KMT2A-Rearranged AML Patients
时间:Monday, December 9, 2024: 3:15 PM
报告人:Yibo Wu
摘要号:425
英文标题:β2-Adrenergic Receptor Agonist Terbutaline Regulates Macrophage Polarization Via HMGB1 in Immune Thrombocytopenia
时间:Sunday, December 8, 2024: 10:30 AM
报告人:Qiuyu Guo
摘要号:426
英文标题:Differentiation Route Generates Functional Biased Platelets and Responses Distinctly to Varying Physiological Demands
时间:Sunday, December 8, 2024: 10:45 AM
报告人:Jingkun Liu
摘要号:266
英文标题:Elevated Dosing of Recombinant Human Thrombopoietin Accelerates Platelet Engraftment in Allogeneic Hematopoietic Stem Cell Transplantation: A Prospective, Dosage-Optimization, Controlled Clinical Study
时间:Saturday, December 7, 2024: 2:15 PM
报告人:Dan Feng
摘要号:268
英文标题:Epstein-Barr Virus Reactivation and Post-Transplant Lymphoproliferative Disorders after Allo-HSCT in the Era of Letermovir for Cytomegalovirus Prophylaxis
时间:Saturday, December 7, 2024: 2:45 PM
报告人:Jingtao Huang
摘要号:270
英文标题:Safety and Efficacy of VA Combined with Modified BuCy Conditioning Regimen Followed By Allo-HSCT for High-Risk or Refractory/Relapsed Acute Lymphoblastic Leukemia : A Prospective, Single-Center, Single-Arm Clinical Trial
时间:Saturday, December 7, 2024: 3:15 PM
报告人:Xiaoqian Chen
摘要号:164
英文标题:Reconstruction of Megaloblastic Anemia in a Novel Erythroblastic Island Humanized Mouse Model with Mature Circulating Human Red Blood Cells
时间:Saturday, December 7, 2024: 2:15 PM
报告人:Shuang Liu
摘要号:690
英文标题:Parvovirus B19 Originates from Infected Hematopoietic Stem Cells Following Hematopoietic Stem Cell Transplantation
时间:Sunday, December 8, 2024: 5:45 PM
报告人:Xuying Pei
摘要号:971
英文标题:Venetoclax and Decitabine Compared with Standard Intensive Chemotherapy As Induction Therapy in Newly Diagnosed Acute Myeloid Leukemia: Updated Results of a Multicenter, Randomized, Phase 2b Trial
时间:Monday, December 9, 2024: 5:30 PM
报告人:Jing Lu
摘要号:972
英文标题:High-Dose Cytarabine with Idarubicin Versus High-Dose Cytarabine within First Consolidation for Acute Myeloid Leukemia in First Complete Remission: An Open-Label, Multicenter, Randomized, Phase 3 Trial
时间:Monday, December 9, 2024: 5:45 PM
报告人:Zinan Feng
摘要号:576
英文标题:Clinical Implications of CSF-Ctdna Positivity in Newly Diagnosed Diffuse Large B Cell Lymphoma in a Large Cohort
时间:Sunday, December 8, 2024: 1:15 PM
报告人:Jinhua Liang
摘要号:562
英文标题:Procr+ Endothelial Progenitor Cells Modulate Adult Hematopoiesis and Microenvironment Homeostasis Via Notch Signaling
时间:Sunday, December 8, 2024: 12:45 PM
报告人:Chang Xu
摘要号:420
英文标题:A Single-Cell Transcriptomic Atlas of Cytokine Storm in CAR-T Therapy, COVID-19, and SLE
时间:Sunday, December 8, 2024: 10:45 AM
报告人:Xia Li
摘要号:30
英文标题:Clec16a-Mediated Mitophagy Modulates Zebrafish Definitive Hematopoiesis
时间:Saturday, December 7, 2024: 10:45 AM
报告人:Shuyang Cai
摘要号:150
英文标题:Efficient Generation of CAR-T By the First Coacervate-Based Gene Delivery
时间:Saturday, December 7, 2024: 1:15 PM
报告人:Peipei Zhu
摘要号:263
英文标题:Targeting the Hypoxic Microenvironment in Cutaneous Chronic Graft-Versus-Host Disease through PI3Kδ Inhibition
时间:Saturday, December 7, 2024: 3:00 PM
报告人:Yuxi Xu
摘要号:977
英文标题:Faecalibacterium Prausnitzii Confers a Protective Effect Against the Development of NKTCL
时间:Monday, December 9, 2024: 5:30 PM
报告人:Zhuangzhuang Shi
摘要号:452
英文标题:Spatial Architecture of Immune Microenvironment Orchestrating Anti-Lymphoma Immunity and the Response to Immunochemotherapy in EBV+ Diffused Large B Cell Lymphoma Revealed By Imaging Mass Cytometry and Spatial Transcriptome
时间:Sunday, December 8, 2024: 9:45 AM
报告人:Zhijuan Lin
摘要号:156
英文标题:Potent in Vitro and In Vivo Efficacy of Hdz-C123A, a GSPT1 Degrader-Antibody Conjugate Targeting CD123 in Acute Myeloid Leukemia
时间:Saturday, December 7, 2024: 1:15 PM
报告人:Yu Guo
摘要号:599
英文标题:Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation Improved Prognosis for Advanced NK/T Cell Lymphoma
时间:Sunday, December 8, 2024: 1:00 PM
报告人:Zhihui Li
摘要号:874
英文标题:CD38 Overexpressed Monocytes Play a Critical Role in the Fibrogenesis in Myeloproliferative Neoplasms and Can be Used As a Therapeutic Target to Ameliorate Fibrosis
时间:Monday, December 9, 2024: 3:30 PM
报告人:Bing Li
摘要号:12
英文标题:Rbm38 Regulates Heme Biosynthesis Via Fine-Tuning the RNA Alternative Splicing, Stability and Translation of Porphyrin Metabolic Enzyme Gene Ferrochelatase (Fech)
时间:Saturday, December 7, 2024: 10:45 AM
报告人:Yang Mei
摘要号:192
英文标题:Exploring the Mechanism of Chromatin Spatial Structure Changes and Transcriptional Regulation in Age-Related Clonal Hematopoiesis Caused By DNMT3A Mutations Using Chromatin Capture Technology
时间:Saturday, December 7, 2024: 3:15 PM
报告人:Yujun Dai
摘要号:964
英文标题:CD7 CAR T-Cell Therapy in Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia: A Retrospective Study
时间:Monday, December 9, 2024: 5:15 PM
报告人:Jing PAN
摘要号:696
英文标题:Haploidentical Peripheral Blood Stem Cell Combined with Bone Marrow or Unrelated Cord Blood As Grafts for Acute Leukemia/Myelodysplastic Syndrome: An Open-Label, Multicenter, Randomized, Phase 3 Trial
时间:Sunday, December 8, 2024: 5:45 PM
报告人:Sijian Yu
摘要号:125
英文标题:Imbalanced Expression of TACI Isoforms Regulated By TNFRSF13B Variants Promotes the Progression of Epstein-Barr Virus-Associated Lymphoproliferative Diseases
时间:Saturday, December 7, 2024: 1:00 PM
报告人:Xinyue Deng
摘要号:328
英文标题:Integrative Multi-Omics Analyses Identify a High-Risk Subgroup of Patients with Poor Prognosis in t(8;21) Acute Myeloid Leukemia
时间:Saturday, December 7, 2024: 4:45 PM
报告人:Yu Liu
摘要号:312
英文标题:Efficacy and Safety of Adding Blinatumomab to First-Line Treatment for Chinese Children with B-Cell Acute Lymphoblastic Leukemia
时间:Saturday, December 7, 2024: 5:15 PM
报告人:Ruidong Zhang
摘要号:904
英文标题:CD33 Antibody-Modified Nanoparticles Encapsulated IL-15 Induce ISG15 to Promote MHC I Expression in Leukemia Cells Via Innate Immunity Pathway Inducing Graft-Versus-Leukemia without Aggravating Graft-Versus-Host Disease
时间:Monday, December 9, 2024: 3:30 PM
报告人:Ruowen Wei
摘要号:372
英文标题:Modified Dual CLL1-CD15 and CLL1-CD16 Icar-T Cells for Mitigating Granulocytopenia Toxicities in the Treatment of Acute Myeloid Leukemia
时间:Saturday, December 7, 2024: 5:15 PM
报告人:Rui Zhang
摘要号:743
英文标题:Single-Cell RNA Analysis of Bone Marrow Mononuclear Cells Reveals Abnormal Activation of T Cells and Monocytes, and Identifies CD35 As a Novel Biomarker and Therapeutic Target in Waldenstrom Macroglobulinemia
时间:Monday, December 9, 2024: 11:30 AM
报告人:Hao Sun
摘要号:300
英文标题:Effects of Low-Molecular-Weight Heparin on Pregnancy Outcomes in Protein S Deficiency: A Prospective, Randomized Controlled Phase II Clinical
时间:Saturday, December 7, 2024: 5:15 PM
报告人:Mengtong Zang
摘要号:54
英文标题:Targeting PRMT9 Overcomes Venetoclax Resistance in AML By Modulating Splicing and Inhibiting Translation
时间:Saturday, December 7, 2024: 10:45 AM
报告人:Yang Li
摘要号:498
英文标题:A Phase I Study of a Novel BCMA×CD3 Bispecific Antibody Emb-06 in Relapsed or Refractory Multiple Myeloma
时间:Sunday, December 8, 2024: 10:45 AM
报告人:Peter T. Tan
来源:中国医学论坛报今日血液
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